Lack of evidence that the XqYq pairing tips at meiosis in the mouse show hypersensitivity to DNAse I.

Chromosoma ·Vol. 95 ·No. 4 ·1987-00-00 ·Pages 290-4

Separovic ER, Chandley AC

Abstract

In situ nick translation procedures have been applied to meiotic metaphase I divisions of the normal and XY, Sxr mouse. Unlike in man, where the pairing tips of the XY bivalent show a special sensitivity to DNAse I nicking, no such sensitivity can be detected for either of these types of mouse. Hypersensitivity in the D-band equivalent region of the X chromosome does, however, exist, this site being early replicating in somatic cells and housing the X inactivation centre (Xce).

MeSH Terms

Animals Bone Marrow Cells Deoxyribonuclease I Karyotyping Male Meiosis Metaphase Mice Organ Specificity Protein Biosynthesis Sex Chromosomes/ultrastructure Spermatogonia/cytology Spleen/cytology

Chemicals

Deoxyribonuclease I

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Separovic E R

Chandley A C

References (17)

17 references, click to expand

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Article Info

Journal

Chromosoma

Abbr.

Chromosoma

ISSN

0009-5915

DOI

10.1007/BF00294786

Published

1987-00-00

Pages

290-4

Language

English

Region

Austria

NLM ID

2985138R

Subset

External Links

PubMed source DOI: 10.1007/BF00294786 View journal details

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Lack of evidence that the XqYq pairing tips at meiosis in the mouse show hypersensitivity to DNAse I.

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