Orotic acid excretion in some wild-type strains of Escherichia coli K-12.

Journal of bacteriology ·Vol. 136 ·No. 2 ·1978-11-00 ·Pages 825-7

Womack JE, O'Donovan GA

Abstract

During rapid growth, the excretion of pyrimidines, predominantly uracil, is a common phenomenon in procaryotes and eucaryotes. In Escherichia coli, some K-12 strains excrete orotic acid and not uracil. This is caused by a mutation in the pyrF gene.

MeSH Terms

Escherichia coli/genetics,growth & development,metabolism Genes Mutation Orotic Acid/metabolism Orotidine-5'-Phosphate Decarboxylase/genetics Uracil/metabolism

Chemicals

Uracil Orotic Acid Orotidine-5'-Phosphate Decarboxylase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Womack J E

O'Donovan G A

References (13)

13 references, click to expand

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Proc Natl Acad Sci U S A. 1965 Jun;53(6):1483-9 PMID: 5324623
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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.136.2.825-827.1978

Published

1978-11-00

Pages

825-7

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC218615

Subset

External Links

PubMed source DOI: 10.1128/jb.136.2.825-827.1978 PMC Full Text View journal details

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Orotic acid excretion in some wild-type strains of Escherichia coli K-12.

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