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PMID: 3608187 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

A new simple screening method for the diagnosis of medium chain acyl-CoA dehydrogenase deficiency.

Clinica chimica acta; international journal of clinical chemistry ·Vol. 165 ·No. 1 ·1987-05-29 ·Pages 39-44

Bhuiyan AK, Watmough NJ, Turnbull DM, Aynsley-Green A, Leonard JV, Bartlett K

Abstract

We describe a simple inexpensive method for the detection of octanoyl-carnitine in urine by reverse-phase high performance thin-layer chromatography of the p-bromophenacyl derivative. This method provides a rapid and reliable means for the diagnosis of medium-chain acyl-CoA dehydrogenase deficiency which is suitable for routine laboratory use.

MeSH Terms

Acetylcarnitine/urine Acyl-CoA Dehydrogenases/deficiency Chromatography, Thin Layer Humans

Chemicals

Acetylcarnitine Acyl-CoA Dehydrogenases

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Bhuiyan A K

Watmough N J

Turnbull D M

Aynsley-Green A

Leonard J V

Bartlett K

Article Info

Journal

Clinica chimica acta; international journal of clinical chemistry

Abbr.

Clin Chim Acta

ISSN

0009-8981

DOI

10.1016/0009-8981(87)90216-6

Published

1987-05-29

Pages

39-44

Language

English

Region

Netherlands

NLM ID

1302422

Subset

External Links

PubMed source DOI: 10.1016/0009-8981(87)90216-6 View journal details

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A new simple screening method for the diagnosis of medium chain acyl-CoA dehydrogenase deficiency.

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