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PMID: 3586856 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Why does a sucrose choice reduce the consumption of alcohol in C57BL/6J mice?

Life sciences ·Vol. 40 ·No. 22 ·1987-06-01 ·Pages 2191-4

Gentry RT, Dole VP

Abstract

To determine why animals reject alcohol when offered palatable solutions of sucrose, male C57BL/6J mice were challenged first with 5% sucrose then with 10% sucrose, while given continuous free-access to alcohol and water. The 5% sucrose dramatically reduced the intake of alcohol and increased the intake of total fluid by an average of 7.3 ml/day. The suppression of alcohol intake could not be attributed to a volumetric ceiling since access to 10% sucrose produced a further large increase in total intake (8.8 ml/day). The results support the interpretation that animals consume alcohol for characteristics it shares with sucrose.

MeSH Terms
Alcohol Drinking/physiology Animals Choice Behavior/physiology Feeding Behavior/physiology Male Mice Mice, Inbred C57BL Sucrose
Chemicals
Sucrose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Gentry R T
Dole V P
Article Info
Journal
Life sciences
Abbr.
Life Sci
ISSN
0024-3205
Published
1987-06-01
Pages
2191-4
Language
English
Region
Netherlands
NLM ID
0375521
Subset
IM
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