In vitro antibacterial activity of irloxacin (E-3432) on clinical isolates.

Drugs under experimental and clinical research ·Vol. 13 ·No. 2 ·1987-00-00 ·Pages 75-7

Coll R, Esteve M, Moros M, Xicota MA, Parés J

Abstract

Irloxacin (E-3432) is a new quinolone derivative. In this study, the activity of irloxacin was compared with that of nalidixic acid, norfloxacin and ciprofloxacin against strains of clinical isolates. Irloxacin showed greater in vitro activity than nalidixic acid, similar activity to norfloxacin and lower activity than ciprofloxacin. Against Staphylococcus, the MIC range of E-3432 was 0.06-1 mg/l, better than the other compounds studied.

MeSH Terms

Anti-Bacterial Agents/pharmacology Chemical Phenomena Chemistry Ciprofloxacin/analogs & derivatives,pharmacology Enterobacteriaceae/drug effects Fluoroquinolones Nalidixic Acid/pharmacology Norfloxacin/pharmacology Quinolines/pharmacology

Chemicals

Anti-Bacterial Agents Fluoroquinolones Quinolines pirfloxacin Nalidixic Acid Ciprofloxacin Norfloxacin

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Coll R

Esteve M

Moros M

Xicota M A

Parés J

Article Info

Journal

Drugs under experimental and clinical research

Abbr.

Drugs Exp Clin Res

ISSN

0378-6501

Published

1987-00-00

Pages

75-7

Language

English

Region

Switzerland

NLM ID

7802135

Subset

External Links

PubMed source

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In vitro antibacterial activity of irloxacin (E-3432) on clinical isolates.

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