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PMID: 3574590 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

The solubility controversy of paired helical filaments: a commentary.

Neurochemical research ·Vol. 12 ·No. 1 ·1987-01-00 ·Pages 93-5

Wisniewski HM, Iqbal K, Grundke-Iqbal I, Rubenstein R

Abstract

暂无摘要

MeSH Terms
Aging/pathology Alzheimer Disease/pathology Brain/ultrastructure Cell Fractionation Electrophoresis, Polyacrylamide Gel Humans Molecular Weight Nerve Tissue Proteins/analysis Neurofibrils/analysis,ultrastructure Solubility
Chemicals
Nerve Tissue Proteins
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Wisniewski H M
Iqbal K
Grundke-Iqbal I
Rubenstein R
References (13)
13 references, click to expand
  1. Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition.
    Acta Neuropathol. 1984;62(3):167-77 PMID: 6538056
  2. Paired helical filaments associated with Alzheimer disease are readily soluble structures.
    Brain Res. 1986 Apr 30;372(1):80-8 PMID: 2939924
  3. Ultrastructure of paired helical filaments of Alzheimer's neurofibrillary tangle.
    J Neuropathol Exp Neurol. 1984 Nov;43(6):643-56 PMID: 6542129
  4. Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.
    EMBO J. 1985 Nov;4(11):2757-63 PMID: 4065091
  5. Protein changes in senile dementia.
    Brain Res. 1974 Sep 6;77(2):337-43 PMID: 4604978
  6. Alzheimer's disease: insolubility of partially purified paired helical filaments in sodium dodecyl sulfate and urea.
    Science. 1982 Mar 5;215(4537):1243-5 PMID: 6120571
  7. Alzheimer neurofibrillary tangles: antiserum and immunohistological staining.
    Ann Neurol. 1979 Dec;6(6):532-7 PMID: 394670
  8. Are Alzheimer neurofibrillary tangles insoluble polymers?
    Life Sci. 1986 May 5;38(18):1695-700 PMID: 3702598
  9. Alzheimer paired helical filaments: cross-reacting polypeptide/s normally present in brain.
    Acta Neuropathol. 1985;66(1):52-61 PMID: 2581415
  10. Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins.
    Nature. 1983 Aug 25-31;304(5928):727-30 PMID: 6350889
  11. Paired helical filament antigen in CSF.
    Lancet. 1985 Jul 6;2(8445):35 PMID: 2861469
  12. Alzheimer paired helical filaments: identification of polypeptides with monoclonal antibodies.
    Acta Neuropathol. 1985;68(4):279-83 PMID: 2418620
  13. Alzheimer paired helical filaments: immunochemical identification of polypeptides.
    Acta Neuropathol. 1984;62(4):259-67 PMID: 6428153
Article Info
Journal
Neurochemical research
Abbr.
Neurochem Res
ISSN
0364-3190
DOI
10.1007/BF00971370
Published
1987-01-00
Pages
93-5
Language
English
Region
United States
NLM ID
7613461
Subset
IM
Grants
NIA NIH HHS · AG/NS-04220 · United States
NINDS NIH HHS · NS-17487 · United States
NINDS NIH HHS · NS-18105 · United States
External Links
PubMed source DOI: 10.1007/BF00971370 View journal details
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