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PMID: 3566708 Published · ppublish English Journal Article

A novel acyl-CoA-binding protein from bovine liver. Effect on fatty acid synthesis.

The Biochemical journal ·Vol. 241 ·No. 1 ·1987-01-01 ·Pages 189-92

Mogensen IB, Schulenberg H, Hansen HO, Spener F, Knudsen J

Abstract

Bovine liver was shown to contain a hitherto undescribed medium-chain acyl-CoA-binding protein. The protein co-purifies with fatty-acid-binding proteins, but was, unlike these proteins, unable to bind fatty acids. The protein induced synthesis of medium-chain acyl-CoA esters on incubation with goat mammary-gland fatty acid synthetase. The possible function of the protein is discussed.

MeSH Terms
Animals Carrier Proteins/metabolism,pharmacology Cattle Chromatography, Gel Electrophoresis, Polyacrylamide Gel Fatty Acid Synthases/metabolism Fatty Acid-Binding Proteins Fatty Acids/biosynthesis Female Goats Isoelectric Focusing Lactation/metabolism Liver/metabolism Mammary Glands, Animal/drug effects,enzymology Neoplasm Proteins Pregnancy
Chemicals
Carrier Proteins Fatty Acid-Binding Proteins Fatty Acids Neoplasm Proteins Fatty Acid Synthases
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Mogensen I B
Schulenberg H
Hansen H O
Spener F
Knudsen J
References (14)
14 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj2410189
Published
1987-01-01
Pages
189-92
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1147542
Subset
IM
External Links
PubMed source DOI: 10.1042/bj2410189 PMC Full Text View journal details
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