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PMID: 3566241 Published · ppublish English Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Single-dose ceftriaxone for chancroid.

Antimicrobial agents and chemotherapy ·Vol. 31 ·No. 1 ·1987-01-00 ·Pages 67-9

Bowmer MI, Nsanze H, D'Costa LJ, Dylewski J, Fransen L, Piot P, Ronald AR

Abstract

Men with genital ulcers that were culture positive for Haemophilus ducreyi were treated with intramuscular ceftriaxone and randomized to three different dose regimens. All but 1 of 50 men treated with 1 g of intramuscular ceftriaxone were cured. Similarly, 0.5 and 0.25 g cured 43 of 44 men and 37 of 38 men, respectively. A single dose of 250 mg of intramuscular ceftriaxone is an effective treatment for chancroid.

MeSH Terms
Adult Ceftriaxone/administration & dosage,therapeutic use Chancroid/drug therapy Drug Administration Schedule Humans Injections, Intramuscular Male Random Allocation
Chemicals
Ceftriaxone
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Bowmer M I
Nsanze H
D'Costa L J
Dylewski J
Fransen L
Piot P
Ronald A R
References (12)
12 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.31.1.67
Published
1987-01-00
Pages
67-9
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC174653
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.31.1.67 PMC Full Text View journal details
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