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PMID: 3539925 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

uvrC gene function has no specific role in repair of N-2-aminofluorene adducts.

Journal of bacteriology ·Vol. 169 ·No. 1 ·1987-01-00 ·Pages 423-6

Bichara M, Fuchs RP

Abstract

In Escherichia coli, plasmid DNA modified with N-2-aminofluorene adducts survived equally well in wild-type, uvrA, or uvrB strains. Increased sensitivity was found in uvrC and uvrD strains. Moreover, N-2-aminofluorene-mediated toxicity in the uvrC background was reversed when an additional uvrA mutation was introduced into the strain.

MeSH Terms
DNA Repair DNA, Bacterial/drug effects Escherichia coli/genetics Fluorenes/toxicity Mutation
Chemicals
DNA, Bacterial Fluorenes 2-aminofluorene
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bichara M
Fuchs R P
References (31)
31 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.169.1.423-426.1987
Published
1987-01-00
Pages
423-6
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC211786
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.169.1.423-426.1987 PMC Full Text View journal details
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