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PMID: 349354 Published · ppublish English Comparative Study Journal Article

Tn951: a new transposon carrying a lactose operon.

Molecular & general genetics : MGG ·Vol. 160 ·No. 2 ·1978-04-06 ·Pages 215-24

Cornelis G, Ghosal D, Saedler H

Abstract

A new transposon, Tn951, is described, which derives from plasmid pGC1, originally isolated from Yersinia enterocolitica. Tn951 is 16.6 kb long and presumably flanked by small inverted repeats. It carries the lac genes i, z and y. This lac system is homologous to the E. coli lac operon. However, homology is restricted to 5.6 kb. The DNA sequences surrounding the lac operons on Tn951 and E. coli are nonhomologous. This leads to speculations about the origin of the E. coli lac operon itself.

MeSH Terms
Base Sequence DNA, Bacterial/analysis Escherichia coli Genes Lactose/metabolism Plasmids Yersinia/genetics,isolation & purification
Chemicals
DNA, Bacterial Lactose
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Cornelis G
Ghosal D
Saedler H
References (25)
25 references, click to expand
  1. Restriction of DNA in Yersinia enterocolitica detected by recipient ability for a derepressed R factor from Escherichia coli.
    J Gen Microbiol. 1975 Apr;87(2):285-91 PMID: 1095683
  2. DRUG RESISTANCE OF ENTERIC BACTERIA. IV. ACTIVE TRANSDUCING BACTERIOPHAGE P1 CM PRODUCED BY THE COMBINATION OF R FACTOR WITH BACTERIOPHAGE P1.
    J Bacteriol. 1964 Nov;88:1266-76 PMID: 14234780
  3. Isolation and characterization of circular deoxyribonucleic acid obtained from lactose-fermenting Salmonella strains.
    J Bacteriol. 1973 Dec;116(3):1185-90 PMID: 4584803
  4. Structural evolution of bacterial plasmids: role of translocating genetic elements and DNA sequence insertions.
    Fed Proc. 1976 Jul;35(9):2031-6 PMID: 776704
  5. Properties of a R factor which originated in Pseudomonas aeruginosa 1822.
    J Bacteriol. 1972 May;110(2):529-37 PMID: 4336689
  6. Transposition of a deoxyribonucleic acid sequence encoding trimethoprim and streptomycin resistances from R483 to other replicons.
    J Bacteriol. 1976 Mar;125(3):800-10 PMID: 767328
  7. Transposition of R factor genes to bacteriophage lambda.
    Proc Natl Acad Sci U S A. 1975 Sep;72(9):3628-32 PMID: 1059152
  8. Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium. I. Transduction of R factor 222 by phage P22.
    Virology. 1972 Dec;50(3):874-82 PMID: 4565617
  9. Multiple copies of the insertion-DNA sequences IS1 and IS2 in the chromosome of E. coli K-12.
    Mol Gen Genet. 1973 May 9;122(3):267-77 PMID: 4577900
  10. Transposition of ampicillin resistance from RP4 to other replicons.
    Mol Gen Genet. 1974;132(1):31-40 PMID: 4609125
  11. Electron microscope heteroduplex studies of sequence relations among bacterial plasmids: identification and mapping of the insertion sequences IS1 and IS2 in F and R plasmids.
    J Bacteriol. 1975 May;122(2):764-75 PMID: 1092668
  12. Occurrence of insertion sequence (IS) regions on plasmid deoxyribonucleic acid as direct and inverted nucleotide sequence duplications.
    J Bacteriol. 1975 May;122(2):776-81 PMID: 1092669
  13. A molecular analysis of transductional marker rescue involving P-group plasmids in Pseudomonas aeruginosa.
    Mol Gen Genet. 1976 Feb 2;143(3):333-7 PMID: 814405
  14. Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. I. Structure of F-prime factors.
    J Mol Biol. 1972 Nov 14;71(2):471-97 PMID: 4564488
  15. Two insertions in the galactose operon having different sizes but homologous DNA sequences.
    Mol Gen Genet. 1969 Aug 15;104(4):371-7 PMID: 4904509
  16. Beginning a genetic analysis of conjugational transfer determined by the F factor in Escherichia coli by isolation and characterization of transfer-deficient mutants.
    J Bacteriol. 1971 May;106(2):529-38 PMID: 4929865
  17. Properties of pGC1, a lac plasmid orginating in Yersinia enterocolitica 842.
    J Bacteriol. 1976 Sep;127(3):1058-62 PMID: 956120
  18. Characterization of a translocation unit encoding resistance to mercuric ions that occurs on a nonconjugative plasmid in Pseudomonas aeruginosa.
    J Bacteriol. 1977 Mar;129(3):1227-33 PMID: 403173
  19. Recalibrated linkage map of Escherichia coli K-12.
    Bacteriol Rev. 1976 Mar;40(1):116-67 PMID: 773363
  20. Expression and regulation of lactose genes carried by plasmids.
    J Bacteriol. 1976 Aug;127(2):691-7 PMID: 783115
  21. IS-elements in microorganisms.
    Curr Top Microbiol Immunol. 1976;75:111-52 PMID: 797531
  22. Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors.
    J Mol Biol. 1973 Apr 5;75(2):235-55 PMID: 4580676
  23. Site specific recA--independent recombination between bacterial plasmids: involvement of palindromes at the recombinational loci.
    Proc Natl Acad Sci U S A. 1975 Apr;72(4):1373-7 PMID: 1093180
  24. The chromosomal integration of a -lactamase gene derived from the P-type R-factor RP1 in Escherichia coli.
    Genet Res. 1972 Oct;20(2):231-7 PMID: 4569692
  25. Physical mapping of a DNA sequence common to plasmids of incompatibility group F I.
    Proc Natl Acad Sci U S A. 1977 Mar;74(3):1190-4 PMID: 322149
Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00267484
Published
1978-04-06
Pages
215-24
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00267484
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