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PMID: 3478708 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Spin glasses and the statistical mechanics of protein folding.

Bryngelson JD, Wolynes PG

Abstract

The theory of spin glasses was used to study a simple model of protein folding. The phase diagram of the model was calculated, and the results of dynamics calculations are briefly reported. The relation of these results to folding experiments, the relation of these hypotheses to previous protein folding theories, and the implication of these hypotheses for protein folding prediction schemes are discussed.

MeSH Terms
Kinetics Mathematics Models, Theoretical Protein Conformation Proteins Stochastic Processes
Chemicals
Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bryngelson J D
Noyes Laboratory, University of Illinois, Urbana 61801.
Wolynes P G
References (16)
16 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1987-11-00
Pages
7524-8
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC299331
Subset
IM
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