A new translocation t(1;4;11) in congenital acute nonlymphocytic leukemia (acute myeloblastic leukemia).

Human genetics ·Vol. 76 ·No. 1 ·1987-05-00 ·Pages 106-8

Selypes A, László A

Abstract

A new translocation t(1;11;4)(1pter----1p32::11q23----11q13::4p16--- -4qter) was found in the peripheral blood of a patient with congenital acute myeloblastic leukemia (AML). It was concluded that this translocation may represent a new mutation, which caused the leukemia with very high leukocytosis, hepatosplenomegaly, leukemic infiltration of the majority of the organs, and a very poor prognosis.

MeSH Terms

Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 11 Chromosomes, Human, Pair 4 Female Genetic Markers Humans Infant Karyotyping Leukemia, Myeloid, Acute/congenital,genetics Translocation, Genetic

Chemicals

Genetic Markers

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Selypes A

László A

References (9)

9 references, click to expand

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Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00283060

Published

1987-05-00

Pages

106-8

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00283060 View journal details

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A new translocation t(1;4;11) in congenital acute nonlymphocytic leukemia (acute myeloblastic leukemia).

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