Glutathione-dependent synthesis of deoxyribonucleotides. Characterization of the enzymatic mechanism of Escherichia coli glutaredoxin.

Bacterial Proteins/metabolism Deoxyribonucleotides/biosynthesis Dithiothreitol/pharmacology Escherichia coli/metabolism Glutathione/metabolism Kinetics NADP Oxidation-Reduction Ribonucleotide Reductases/metabolism Structure-Activity Relationship Sulfhydryl Compounds/pharmacology Thioredoxins/metabolism

Bacterial Proteins Deoxyribonucleotides Sulfhydryl Compounds Thioredoxins NADP Ribonucleotide Reductases Glutathione Dithiothreitol