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PMID: 3448155 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Streptomyces albus G produces an antibiotic complex identical to paulomycins A and B.

Journal of general microbiology ·Vol. 133 ·No. 9 ·1987-09-00 ·Pages 2503-7

Majer J, Chater KF

Abstract

An antibiotic complex active against multiply resistant strains of staphylococci and other Gram-positive bacteria was isolated from cultures of Streptomyces albus G. Silica gel and Sephadex LH-20 column chromatography gave two congeners with Mr values of 786 and 772, which differed by one -CH2-group. The two homologues contained an isothiocyanate group, and proved to be identical with paulomycins A and B produced by Streptomyces paulus; the FAB mass spectra, in addition, proved the same two congeners to be present in proceomycin obtained from Streptomyces alboniger.

MeSH Terms
Anti-Bacterial Agents/biosynthesis Disaccharides/biosynthesis Drug Resistance, Microbial Mass Spectrometry Streptomyces/metabolism
Chemicals
Anti-Bacterial Agents Disaccharides paulomycin B paulomycin A
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Majer J
Northwestern University Medical School, Chicago, Illinois 60611.
Chater K F
Article Info
Journal
Journal of general microbiology
Abbr.
J Gen Microbiol
ISSN
0022-1287
Published
1987-09-00
Pages
2503-7
Language
English
Region
England
NLM ID
0375371
Subset
IM
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