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PMID: 3448154 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Biotransformation of 3-methylphthalate by Micrococcus sp. strain 12B.

Journal of general microbiology ·Vol. 133 ·No. 9 ·1987-09-00 ·Pages 2473-6

Eaton RW, Ribbons DW

Abstract

When Micrococcus strain 12B grown on o-phthalate was incubated with 3-methylphthalate, three compounds accumulated. These were shown to be 2-pyrone-3-methyl-4,6-dicarboxylic acid, 3,4-dihydroxy-6-methylphthalic acid, and 5-hydroxy-3-methyphthalic acid, all previously undescribed. A pathway for the formation of these compounds is proposed.

MeSH Terms
Biotransformation Chromatography, Gel Micrococcus/metabolism Phthalic Acids/pharmacokinetics
Chemicals
Phthalic Acids 3-methylphthalate
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Eaton R W
Department of Microbiology, University of Miami School of Medicine, Florida 33152.
Ribbons D W
Article Info
Journal
Journal of general microbiology
Abbr.
J Gen Microbiol
ISSN
0022-1287
DOI
10.1099/00221287-133-9-2473
Published
1987-09-00
Pages
2473-6
Language
English
Region
England
NLM ID
0375371
Subset
IM
Grants
NCEH CDC HHS · EHS 00986 · United States
NIGMS NIH HHS · GM 20172 · United States
External Links
PubMed source DOI: 10.1099/00221287-133-9-2473
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