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题目:: A cytological procedure to screen mammalian temperature-sensitive mutants for cell-cycle-related defects.
作者:: Moser(G C),Meiss(H K)
状态:: 发布时间1978-03-29 , 更新时间 2013-11-21
期刊:: Somatic Cell Genet
摘要:: Interphase cells stained with quinacrine dihydrochloride show distinctive fluorescent nuclear patterns according to their position in the cell cycle. These patterns were used to determine whether temperature-sensitive growth mutants of the Syrian hamster cell line BHK-21 are blocked at specific stages of the cell cycle. These cytological studies confirmed the previous conclusion that ts Af8 cell line derived from BHK cells is a GI cell-cycle mutant. The method promises to be of use as an initial probe in screening for cell-cycle mutants.
语言:: eng
DOI:

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