UV-sensitivity and repair of UV-damages in Salmonella of wild type.

Molecular & general genetics : MGG ·Vol. 158 ·No. 2 ·1977-12-30 ·Pages 211-4

Kondratiev YS, Brukhansky GV, Andreeva IV, Skavronskaya AG

Abstract

The UV-sensitivity of wild type Salmonella strains has been compared to that of wild type E. cole and its UV-sensitive mutants. Many wild type Salmonella strains are 4-5 times more sensitive than wild type E. coli and their inactivation curves is similar to that for E. coli with a mutation in the polA gene. Alkaline sucrose gradient centrifugation has shown a deficiency of these strains in normal excision repair of UV-damaged DNA. This deficiency is not a Salmonella genus feature because one strain as resistant as wild type E. coli was found. This resistant strain showed normal excision repair in alkaline sucrose gradient centrifugation experiments. The possible influence of plasmids and mutations in repair genes on the ability of Salmonella to repair UV-damages DNA is discussed.

MeSH Terms

DNA Repair DNA, Bacterial/radiation effects Escherichia coli/radiation effects Mutation Radiation Tolerance Salmonella/radiation effects Ultraviolet Rays

Chemicals

DNA, Bacterial

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Kondratiev Y S

Brukhansky G V

Andreeva I V

Skavronskaya A G

References (17)

17 references, click to expand

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Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF00268315

Published

1977-12-30

Pages

211-4

Language

English

Region

Germany

NLM ID

0125036

Subset

External Links

PubMed source DOI: 10.1007/BF00268315

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UV-sensitivity and repair of UV-damages in Salmonella of wild type.

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