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PMID: 339105 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone.

Nature ·Vol. 270 ·No. 5637 ·1977-12-08 ·Pages 486-94

Seeburg PH, Shine J, Martial JA, Baxter JD, Goodman HM

Abstract

The primary structure of DNA containing the sequence for rat pituitary growth hormone mRNA has been determined. DNA was obtained by reverse transcription of polyadenylated RNA from cultured pituitary cells and from recombinant bacterial plasmids. The amino acid sequences for rat growth hormone and its precursor form have been deduced from the determined nucleotide sequences.

MeSH Terms

Amino Acid Sequence Animals Base Sequence Chromosome Mapping DNA, Recombinant Escherichia coli/genetics Genes Growth Hormone/genetics Plasmids Protein Precursors/genetics RNA, Messenger/genetics Rats

Chemicals

DNA, Recombinant Protein Precursors RNA, Messenger Growth Hormone

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Seeburg P H

Shine J

Martial J A

Baxter J D

Goodman H M

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/270486a0

Published

1977-12-08

Pages

486-94

Language

English

Region

England

NLM ID

0410462

Subset

Databases

GENBANK

J00789

External Links

PubMed source DOI: 10.1038/270486a0 View journal details

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Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone.

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