Transposable genetic elements as agents of gene instability and chromosomal rearrangements.

Nature ·Vol. 268 ·No. 5616 ·1977-07-14 ·Pages 109-15

Nevers P, Saedler H

Abstract

Transposable genetic elements in prokaryotes and eukaryotes, when inserted at a given locus, can control expression of the locus and cause large scale rearrangements of adjacent DNA sequences. Striking similarities in genetic behaviour between the two groups of elements have led to the proposal of a molecular model of eukaryotic controlling elements, and to suggestions about the part such elements may play in evolution and differentiation.

MeSH Terms

Base Sequence Chromosome Aberrations Chromosome Deletion Chromosome Mapping DNA, Bacterial/genetics Escherichia coli/genetics Eukaryotic Cells/ultrastructure Genes Mutation Operon Periodicity Phenotype Prokaryotic Cells/ultrastructure Suppression, Genetic Zea mays/genetics

Chemicals

DNA, Bacterial

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Nevers P

Saedler H

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/268109a0

Published

1977-07-14

Pages

109-15

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/268109a0 View journal details

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Transposable genetic elements as agents of gene instability and chromosomal rearrangements.

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