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PMID: 3352221 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Allelic profile at 37 biochemical loci of two inbred strains of the house mouse derived from wild Mus musculus musculus.

Laboratory animals ·Vol. 22 ·No. 1 ·1988-01-00 ·Pages 61-6

von Deimling OH, Forejt J, Wienker TF

Abstract

Two newly established inbred strains derived from Mus musculus musculus, designated PWD/Ph (F29) and PWK/Ph (F33), were examined for their alleles at 37 biochemical loci located on 12 different chromosomes. The allelic pattern showed characteristic differences from those observed in common inbred strains. The genetic distance D between PWK/Ph and PWD/Ph was 0.027, whereas the corresponding values for the genetic distances between PWK/Ph and C57BL/6J, DBA/2J, BALB/cJ and SWR/J were 0.777, 0.721, 0.721 and 0.838 respectively. New allozymes are described as being controlled by the loci Es-23, Pre-2 and Tam-1. The genetic relationship to M.m.molossinus is indicated by identical alleles at six other loci (Es-2, Es-9, Es-10, Es-11, Es-18 and Es-22).

MeSH Terms
Alleles Animals Chromosome Mapping Electrophoresis, Disc Esterases/genetics Female Male Mice Mice, Inbred Strains/genetics
Chemicals
Esterases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
von Deimling O H
Abteilung Chemische Pathologie, Universität Freiburg, Federal Republic of Germany.
Forejt J
Wienker T F
Article Info
Journal
Laboratory animals
Abbr.
Lab Anim
ISSN
0023-6772
Published
1988-01-00
Pages
61-6
Language
English
Region
England
NLM ID
0112725
Subset
IM
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