Cell cycle of Saccharomycescerevisiae in populations growing at different rates.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 74 ·No. 9 ·1977-09-00 ·Pages 3850-4

Slater ML, Sharrow SO, Gart JJ

Abstract

The cell cycle of Saccharomyces cerevisiae in populations growing at different rates was analyzed by flow microflourometry. The results demonstrate that (i) variation in growth rate of the population depends mainly on variation in the G1 phase of the cell cycle, and (ii) atall growth rates initiation of DNA synthesis occurs concomitantly with initiation of budding.

MeSH Terms

Cell Cycle/drug effects Cycloheximide/pharmacology DNA/biosynthesis DNA Replication Mathematics Mitosis Models, Biological Saccharomyces cerevisiae/physiology

Chemicals

DNA Cycloheximide

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Slater M L

Sharrow S O

Gart J J

References (13)

13 references, click to expand

LIFE CYCLE ANALYSIS OF MAMMALIAN CELLS. I. A METHOD FOR LOCALIZING METABOLIC EVENTS WITHIN THE LIFE CYCLE, AND ITS APPLICATION TO THE ACTION OF COLCEMIDE AND SUBLETHAL DOSES OF X-IRRADIATION.
Biophys J. 1963 Sep;3:379-97 PMID: 14062457
Growth rates of individual yeast cells.
Genetica. 1954;27(1-2):45-53 PMID: 13183341
Autoradiographic analysis of regional cell wall growth of yeasts. III. Saccharomyces cerevisiae.
Exp Cell Res. 1966 Mar;41(3):580-91 PMID: 4952856
Role of protein synthesis in the replication of yeast DNA.
Nat New Biol. 1973 Aug 1;244(135):129-31 PMID: 4579463
Unique techniques for cell analysis utilizing mithramycin and flow microfluorometry.
Exp Cell Res. 1975 Jun;93(1):235-9 PMID: 49273
The timing of deoxyribonucleic acid synthesis in the cell cycle of Saccharomyces cerevisiae.
J Cell Biol. 1965 Jun;25(3):517-28 PMID: 4284570
Effect of growth rate on the amounts of ribosomal and transfer ribonucleic acids in yeast.
J Bacteriol. 1975 Jun;122(3):855-65 PMID: 1097403
Saccharomyces cerevisiae cell cycle.
Bacteriol Rev. 1974 Jun;38(2):164-98 PMID: 4599449
The cell cycle and the control of cellular reproduction.
Adv Genet. 1976;18:99-177 PMID: 181964
On the bacterial life sequence.
Cold Spring Harb Symp Quant Biol. 1968;33:809-22 PMID: 4892010
Genetic control of the cell-division cycle in yeast. I. Detection of mutants.
Proc Natl Acad Sci U S A. 1970 Jun;66(2):352-9 PMID: 5271168
[The budding cycle of Saccharomyces cerevisiae].
Pathol Microbiol (Basel). 1968;31(2):117-27 PMID: 5650638
Effects of temperature on growth rate of cultured mammalian cells (L5178Y).
J Cell Biol. 1967 Feb;32(2):309-23 PMID: 10976224

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.74.9.3850

Published

1977-09-00

Pages

3850-4

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC431757

Subset

External Links

PubMed source DOI: 10.1073/pnas.74.9.3850 PMC Full Text View journal details

Analysis Services

Cell cycle of Saccharomycescerevisiae in populations growing at different rates.

Contact

WeChat Official Account