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PMID: 33187 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Inhibition of glutathione biosynthesis by prothionine sulfoximine (S-n-propyl homocysteine sulfoximine), a selective inhibitor of gamma-glutamylcysteine synthetase.

The Journal of biological chemistry ·Vol. 254 ·No. 4 ·1979-02-25 ·Pages 1205-10

Griffith OW, Anderson ME, Meister A

Abstract

暂无摘要

MeSH Terms

Animals Binding Sites Glutamate-Cysteine Ligase/antagonists & inhibitors Glutamine/metabolism Glutathione/biosynthesis Kidney/metabolism Kinetics Methionine Sulfoximine/analogs & derivatives,pharmacology Peptide Synthases/antagonists & inhibitors Rats Structure-Activity Relationship

Chemicals

Glutamine Methionine Sulfoximine prothionine sulfoximine Peptide Synthases Glutamate-Cysteine Ligase Glutathione

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Griffith O W

Anderson M E

Meister A

Article Info

Journal

The Journal of biological chemistry

Abbr.

J Biol Chem

ISSN

0021-9258

Published

1979-02-25

Pages

1205-10

Language

English

Region

United States

NLM ID

2985121R

Subset

External Links

PubMed source View journal details

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Inhibition of glutathione biosynthesis by prothionine sulfoximine (S-n-propyl homocysteine sulfoximine), a selective inhibitor of gamma-glutamylcysteine synthetase.

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