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PMID: 3312636 Published · ppublish English Journal Article

Expression of envelope glycoproteins of human immunodeficiency virus by an insect virus vector.

Journal of virology ·Vol. 61 ·No. 11 ·1987-11-00 ·Pages 3617-20

Hu SI, Kosowski SG, Schaaf KF

Abstract

The envelope gene of human immunodeficiency virus was inserted into the genome of an insect virus vector (Autographa californica nuclear polyhedrosis virus). Upon infection of tissue culture cells, this recombinant virus produced immunoreactive polypeptides related to the envelope glycoproteins of human immunodeficiency virus. Serological survey indicates such polypeptides would be of value as antigens in diagnostics for acquired immunodeficiency syndrome.

MeSH Terms
Animals Cloning, Molecular Genes Genes, Viral Genetic Vectors HIV/genetics Insect Viruses/genetics Insecta Viral Envelope Proteins/analysis,genetics
Chemicals
Viral Envelope Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hu S I
Oncogen System Corporation, Seattle, Washington 98121.
Kosowski S G
Schaaf K F
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.61.11.3617-3620.1987
Published
1987-11-00
Pages
3617-20
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC255964
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.61.11.3617-3620.1987 PMC Full Text View journal details
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