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PMID: 3312170 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Identification of Treponema pallidum penicillin-binding proteins.

Journal of bacteriology ·Vol. 169 ·No. 11 ·1987-11-00 ·Pages 5298-300

Cunningham TM, Miller JN, Lovett MA

Abstract

Penicillin-binding proteins of 180, 89, 80, 68, 61, 41, and 38 kilodaltons were identified in Treponema pallidum (Nichols) by their covalent binding of [35S]benzylpenicillin. Penicillin-binding proteins are localized in the plasma membranes of many bacterial species and may serve as useful markers for determining plasma membrane intactness in T. pallidum fractionation studies.

MeSH Terms
Bacterial Proteins Carrier Proteins/isolation & purification,metabolism Electrophoresis, Polyacrylamide Gel Hexosyltransferases Molecular Weight Muramoylpentapeptide Carboxypeptidase/isolation & purification,metabolism Penicillin G/metabolism Penicillin-Binding Proteins Peptidyl Transferases Treponema pallidum/metabolism
Chemicals
Bacterial Proteins Carrier Proteins Penicillin-Binding Proteins Peptidyl Transferases Hexosyltransferases Muramoylpentapeptide Carboxypeptidase Penicillin G
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Cunningham T M
Department of Microbiology and Immunology, School of Medicine, University of California, Los Angeles 90024.
Miller J N
Lovett M A
References (17)
17 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.169.11.5298-5300.1987
Published
1987-11-00
Pages
5298-300
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC213939
Subset
IM
Grants
NIAID NIH HHS · AI-12601 · United States
NIAID NIH HHS · AI-21352 · United States
External Links
PubMed source DOI: 10.1128/jb.169.11.5298-5300.1987 PMC Full Text View journal details
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