Beta-lipotropin and endorphins: implications of current knowledge.

Hospital practice ·Vol. 13 ·No. 11 ·1978-11-00 ·Pages 53-60

Guillemin R

Abstract

Evidence that the endorphins, metabolites of the pituitary hormone beta-lipotropin, profoundly affect mood and behavior, are secreted with ACTH in response to stress, and may act as neurotransmitters in the GI tract, suggests that they play an important role in CNS homeostasis. The fact that these peptides are synthesized in the GI tract as well as the brain casts new light on CNS-endocrine-environmental interrelationships.

MeSH Terms

Adrenocorticotropic Hormone/metabolism Animals Brain/metabolism Corticosterone/blood Digestive System/metabolism Endorphins/metabolism,physiology Homeostasis Humans Hypothalamus/metabolism Mice Neurotransmitter Agents/metabolism Pituitary Gland/metabolism Rats Stress, Physiological beta-Lipotropin/metabolism

Chemicals

Endorphins Neurotransmitter Agents Adrenocorticotropic Hormone beta-Lipotropin Corticosterone

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Guillemin R

Article Info

Journal

Hospital practice

Abbr.

Hosp Pract

ISSN

0018-5809

DOI

10.1080/21548331.1978.11707431

Published

1978-11-00

Pages

53-60

Language

English

Region

United States

NLM ID

0074404

Subset

External Links

PubMed source DOI: 10.1080/21548331.1978.11707431

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Beta-lipotropin and endorphins: implications of current knowledge.

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