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PMID: 32908 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Delta14-sterol reductase in Saccharomyces cerevisiae.

Biochimica et biophysica acta ·Vol. 531 ·No. 3 ·1978-12-22 ·Pages 301-7

Bottema CK, Parks LW

Abstract

An in vitro assay for delta14-sterol reductase from yeast was developed, using ergosta-8,14-dien-3beta-ol as the substrate. The kinetics and localization of the enzyme were examined. The inhibition of the enzyme by the antimycotic agent, 15-azasterol, was verified.

MeSH Terms

Cholestadienols/pharmacology Ergosterol/analogs & derivatives Hydrogen-Ion Concentration Kinetics Oxidoreductases/antagonists & inhibitors,metabolism Saccharomyces cerevisiae/enzymology Subcellular Fractions/enzymology

Chemicals

Cholestadienols Oxidoreductases Ergosterol

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Bottema C K

Parks L W

Article Info

Journal

Biochimica et biophysica acta

Abbr.

Biochim Biophys Acta

ISSN

0006-3002

DOI

10.1016/0005-2760(78)90212-6

Published

1978-12-22

Pages

301-7

Language

English

Region

Netherlands

NLM ID

0217513

Subset

External Links

PubMed source DOI: 10.1016/0005-2760(78)90212-6

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Delta14-sterol reductase in Saccharomyces cerevisiae.

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