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PMID: 3285892 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Transcending the impenetrable: how proteins come to terms with membranes.

Biochimica et biophysica acta ·Vol. 947 ·No. 2 ·1988-06-09 ·Pages 307-33

von Heijne G

Abstract

In the living cell, proteins are efficiently sorted to a whole range of subcellular compartments. In many cases, sorting specificity is mediated by short 'sorting signals' attached either permanently or transiently to the protein. At long last, a fairly coherent picture of the design and function of many such sorting signals is beginning to emerge.

MeSH Terms

Algorithms Cell Compartmentation Cell Membrane/metabolism Lipid Bilayers/metabolism Membrane Lipids/metabolism Models, Biological Models, Molecular Protein Sorting Signals/physiology Proteins/metabolism

Chemicals

Lipid Bilayers Membrane Lipids Protein Sorting Signals Proteins

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

von Heijne G

Department of Molecular Biology, Karolinska Institutet, Huddinge University Hospital, Sweden.

Article Info

Journal

Biochimica et biophysica acta

Abbr.

Biochim Biophys Acta

ISSN

0006-3002

DOI

10.1016/0304-4157(88)90013-5

Published

1988-06-09

Pages

307-33

Language

English

Region

Netherlands

NLM ID

0217513

Subset

External Links

PubMed source DOI: 10.1016/0304-4157(88)90013-5

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