Formation and metabolism of alkylated nucleosides: possible role in carcinogenesis by nitroso compounds and alkylating agents.

Alkylating Agents Animals Base Sequence Carcinogens/pharmacology DNA/biosynthesis,metabolism DNA Restriction Enzymes Ethionine/metabolism,pharmacology Methylation Mutation/drug effects Nitroso Compounds Nucleosides/biosynthesis,metabolism,physiology Protein Biosynthesis RNA/biosynthesis RNA, Messenger/metabolism RNA, Ribosomal/metabolism RNA, Transfer/metabolism S-Adenosylhomocysteine/metabolism S-Adenosylmethionine/metabolism tRNA Methyltransferases/metabolism

Alkylating Agents Carcinogens Nitroso Compounds Nucleosides RNA, Messenger RNA, Ribosomal RNA S-Adenosylmethionine DNA RNA, Transfer S-Adenosylhomocysteine tRNA Methyltransferases DNA Restriction Enzymes Ethionine