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PMID: 323408 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Redistribution of myosin accompanying capping of surface Ig.

The Journal of experimental medicine ·Vol. 145 ·No. 5 ·1977-05-01 ·Pages 1393-8

Schreiner GF, Fujiwara K, Pollard TD, Unanue ER

Abstract

The capping of surface Ig on B cells occurs with a striking redistribution of cytoplasmic myosin. Our results suggest a close association between surface Ig and myosin which could be the basis for Ig redistribution and stimulated motility.

MeSH Terms

Animals B-Lymphocytes/analysis,immunology Cell Membrane/immunology Cytoplasm/immunology Fluorescent Antibody Technique Mice Mice, Inbred A Myosins/analysis Receptors, Antigen, B-Cell Spleen/immunology

Chemicals

Receptors, Antigen, B-Cell Myosins

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Schreiner G F

Fujiwara K

Pollard T D

Unanue E R

References (8)

8 references, click to expand

Fluorescent antibody localization of myosin in the cytoplasm, cleavage furrow, and mitotic spindle of human cells.
J Cell Biol. 1976 Dec;71(3):848-75 PMID: 62755
The disruption of immunoglobulin caps by local anesthetics.
Clin Immunol Immunopathol. 1976 Sep;6(2):264-9 PMID: 1085687
Actin and myosin and cell movement.
CRC Crit Rev Biochem. 1974 Jan;2(1):1-65 PMID: 4273099
Ligand-induced movement of lymphocyte membrane macromolecules. 3. Relationship between the formation and fate of anti-Ig-surface Ig complexes and cell metabolism.
J Exp Med. 1973 Mar 1;137(3):675-89 PMID: 4540168
Distribution of immunoglobulin on the surface of mouse lymphoid cells as determined by immunoferritin electron microscopy. Antibody-induced, temperature-dependent redistribution and its implications for membrane structure.
Eur J Immunol. 1972 Dec;2(6):523-35 PMID: 4654868
Calcium-sensitive modulation of Ig capping: evidence supporting a cytoplasmic control of ligand-receptor complexes.
J Exp Med. 1976 Jan 1;143(1):15-31 PMID: 811752
Concanavalin A receptors, immunoglobulins, and theta antigen of the lymphocyte surface. Interactions with concanavalin A and with Cytoplasmic structures.
J Cell Biol. 1975 Apr;65(1):123-46 PMID: 1092699
Local anesthetics affect transmembrane cytoskeletal control of mobility and distribution of cell surface receptors.
Proc Natl Acad Sci U S A. 1975 Nov;72(11):4430-4 PMID: 1060123

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.145.5.1393

Published

1977-05-01

Pages

1393-8

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2180660

Subset

External Links

PubMed source DOI: 10.1084/jem.145.5.1393 PMC Full Text View journal details

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Redistribution of myosin accompanying capping of surface Ig.

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