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PMID: 320662 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

H-Y antigen: behavior and function.

Science (New York, N.Y.) ·Vol. 195 ·No. 4282 ·1977-03-11 ·Pages 956-60

Silvers WK, Wachtel SS

Abstract

The factors are reviewed which affect the expression of H-Y antigen, a cell surface component that has been extensively analyzed in mice but which may be ubiquitous in all vertebrates. The phylogenetic stability of this antigen and its association with the Y chromosome indicate an important role in primary sex determination.

MeSH Terms

Androgens/physiology Animals Biological Evolution Cytotoxicity Tests, Immunologic Genes Histocompatibility Antigens/analysis Humans Immune Adherence Reaction Immunosorbent Techniques Male Sex Chromosomes Sex Determination Analysis Species Specificity Spermatozoa/immunology Testis/embryology

Chemicals

Androgens Histocompatibility Antigens

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Silvers W K

Wachtel S S

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.320662

Published

1977-03-11

Pages

956-60

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.320662 View journal details

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