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PMID: 320094 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

A genetic fine structure analysis of the suppressor 3 locus in Saccharomyces.

Genetics ·Vol. 85 ·No. 1 ·1977-01-00 ·Pages 55-64

Rothstein RJ

Abstract

A meiotic fine structure map of a yeast tyrosine-inserting ochre suppressor, SUP3-omicron, was constructed. This was accomplished by examining ten intragenic suppressor-inactive revertants for their relationship to each other and to the original SUP3-omicron mutation. The second-site revertants map on both sides of the SUP3-omicron mutation. The meiotic map length based on the summation of short intervals is 45+/10(5) asci.

MeSH Terms
Chromosome Mapping Meiosis Mutation Saccharomyces cerevisiae Spores Suppression, Genetic Tyrosine/metabolism
Chemicals
Tyrosine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Rothstein R J
References (5)
5 references, click to expand
  1. Yeast super-suppressors are altered tRNAs capable of translating a nonsense codon in vitro.
    Cell. 1975 Nov;6(3):269-77 PMID: 802681
  2. Temperature-sensitive nonsense suppressors in yeast.
    Genetics. 1973 Nov;75(3):459-64 PMID: 4590686
  3. Suppressor genes for nonsense mutations. I. The Su-1, Su-2 and Su-3 genes of Escherichia coli.
    J Mol Biol. 1965 Nov;14(1):167-78 PMID: 5327650
  4. Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon.
    Nature. 1976 Aug 26;262(5571):757-61 PMID: 785283
  5. Yeast suppressors of UAA and UAG nonsense codons work efficiently in vitro via tRNA.
    Cell. 1976 Mar;7(3):381-90 PMID: 947546
Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/85.1.55
Published
1977-01-00
Pages
55-64
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1213619
Subset
IM
External Links
PubMed source DOI: 10.1093/genetics/85.1.55 PMC Full Text View journal details
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