Home LiteratureArticle Details
PMID: 3198117 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Glucose-6-phosphate dehydrogenase variants and their frequency in Guangdong, China.

Human genetics ·Vol. 80 ·No. 4 ·1988-12-00 ·Pages 385-8

Du CS, Xu YK, Hua XY, Wu QL, Liu LB

Abstract

Erythrocyte glucose-6-phosphate dehydrogenase (G6PD) was characterized in blood samples obtained from 97 randomly selected males with enzyme deficiency from various regions of Guangdong Province, China. Nine new variants (Gd Kaiping, Gd Boluo, Gd Huiyang, Gd Gaomin, Gd Qing-Baijiang, Gd Gaozhou, Gd Huazhou, Gd Nanhai, and Gd Guangzhou) were identified. Of the 31 variants found in this province, Gd Kaiping, Gd Taiwan-Hakka, Gd Haad Yai, Gd Haad Yai-like and Gd Huiyang occurred most frequently. The frequency of each variant was calculated. The results demonstrated that the genetic heterogeneity of G6PD deficiency was high in this area.

MeSH Terms
China Erythrocytes/enzymology Gene Frequency Glucosephosphate Dehydrogenase/blood,genetics Glucosephosphate Dehydrogenase Deficiency/genetics Humans Male Polymorphism, Genetic
Chemicals
Glucosephosphate Dehydrogenase
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Du C S
Department of Medical Genetics, Sun Yat Sen University of Medical Sciences, Guangzhou, The People's Republic of China.
Xu Y K
Hua X Y
Wu Q L
Liu L B
References (12)
12 references, click to expand
  1. G-6-PD variants in Thailand.
    J Med Assoc Thai. 1980 Oct;63(10):537-43 PMID: 7441068
  2. Variants of glucose-6-phosphate dehydrogenase in a Vietnamese population.
    Hum Hered. 1986;36(6):348-51 PMID: 3793116
  3. G-6-PD variants: another up-date.
    Ann Hum Genet. 1983 Jan;47(Pt 1):25-38 PMID: 6838168
  4. G6PD Ube, a glucose-6-phosphate dehydrogenase variant found in four unrelated Japanese families.
    Am J Hum Genet. 1977 Jan;29(1):24-30 PMID: 835572
  5. Glucose-6-phosphate dehydrogenase deficiency in South Vietnamese.
    Hum Hered. 1980;30(6):361-4 PMID: 7216225
  6. A deficiency of glucose-6-phosphate dehydrogenase activity in erythrocytes from patients with favism.
    Bull Johns Hopkins Hosp. 1958 Apr;102(4):169-75 PMID: 13523280
  7. Characteristics and distribution of glucose-6-phosphate dehydrogenase-deficient variants in South China.
    Am J Hum Genet. 1972 Jul;24(4):475-84 PMID: 5031985
  8. Human glucose-6-phosphate dehydrogenase variants: a supplementary tabulation.
    Ann Hum Genet. 1978 Jan;41(3):347-55 PMID: 626479
  9. A Chinese variant of glucose-6-phosphate dehydrogenase.
    J Lab Clin Med. 1966 Mar;67(3):374-85 PMID: 4379606
  10. Standardization of procedures for the study of glucose-6-phosphate dehydrogenase. Report of a WHO Scientific Group.
    World Health Organ Tech Rep Ser. 1967;366:1-53 PMID: 4963040
  11. Glucose-6-phosphate dehydrogenase deficiency in Papua New Guinea. The description of 13 new variants.
    Hum Genet. 1982;60(2):189-92 PMID: 7076260
  12. Two new glucose-6 phosphate dehydrogenase (G6PD) variants associated with hemolytic anemia: G6PD Amman-1 and G6PD Amman-2.
    Am J Hematol. 1986 Jun;22(2):185-92 PMID: 3706292
Article Info
Journal
Human genetics
Abbr.
Hum Genet
ISSN
0340-6717
DOI
10.1007/BF00273657
Published
1988-12-00
Pages
385-8
Language
English
Region
Germany
NLM ID
7613873
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00273657 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2