Maximal binding levels of an H1 histone gene-specific factor in S-phase correlate with maximal H1 gene transcription.
Levels of trans-acting factor (H1-SF) binding to the histone H1 gene-specific motif (5'-AAACACA-3' [L. S. Coles and J. R. E. Wells, Nucleic Acids Res. 13:585-594, 1985]) increase 12-fold from G1 to S-phase in synchronized cells and decrease again in G2 phase of the cell cycle. Since the H1 element is required for S-phase expression of H1 genes (S. Dalton and J. R. E. Wells, EMBO J. 7:49-56, 1988), it is likely that the increased levels of H1-SF binding component play an important role in S-phase regulation of H1 gene transcription.
12 references, click to expand
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.Anal Biochem. 1976 May 7;72:248-54 PMID: 942051
-
Independently evolving chicken histone H2B genes: identification of a ubiquitous H2B-specific 5' element.Nucleic Acids Res. 1982 Dec 11;10(23):7851-63 PMID: 6296794
-
An H1 histone gene-specific 5' element and evolution of H1 and H5 genes.Nucleic Acids Res. 1985 Jan 25;13(2):585-94 PMID: 4000927
-
Purification and biochemical characterization of the promoter-specific transcription factor, Sp1.Science. 1986 Oct 3;234(4772):47-52 PMID: 3529394
-
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism.Cell. 1986 Dec 26;47(6):921-8 PMID: 3096580
-
A gene-specific promoter element is required for optimal expression of the histone H1 gene in S-phase.EMBO J. 1988 Jan;7(1):49-56 PMID: 2896124
-
Promoters, activator proteins, and the mechanism of transcriptional initiation in yeast.Cell. 1987 May 8;49(3):295-7 PMID: 2882858
-
Cell cycle regulation of SW15 is required for mother-cell-specific HO transcription in yeast.Cell. 1987 May 22;49(4):549-58 PMID: 3552251
-
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor.Cell. 1987 Jun 19;49(6):729-39 PMID: 3034432
-
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements.Cell. 1987 Jun 19;49(6):741-52 PMID: 3034433
-
Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene.Cell. 1987 Dec 4;51(5):773-81 PMID: 3677172
-
Transcription of the histone H5 gene is not S-phase regulated.Mol Cell Biol. 1986 Feb;6(2):601-6 PMID: 3785154
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: product@genelibs.com
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
