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PMID: 3143621 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Studies of the genetic organization of the vestigial microregion of Drosophila melanogaster.

Genetics ·Vol. 120 ·No. 2 ·1988-10-00 ·Pages 495-502

Lasko PF, Pardue ML

Abstract

The region of the second chromosome of Drosophila melanogaster defined by Df(2R)vgB was screened for recessive lethal and visible mutations. Fifty-eight new recessive alleles fall into 17 complementation groups. Many new vg alleles were also isolated in a screen for new vg deficiencies. The breakpoints of the new vg deficiencies were nonrandomly distributed. The distal breakpoints of twelve of 20 deficiencies overlapping Df(2R)vgB are genetically identical to that of Df(2R)vgD, coinciding with the position of a complex, pleiotropic locus, l(2)49Ea-Psc-Su(z)2.

MeSH Terms
Alleles Animals Chromosome Mapping Drosophila melanogaster/genetics Genes, Lethal Genes, Recessive Genetic Complementation Test Mutation
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Lasko P F
Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.
Pardue M L
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Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/120.2.495
Published
1988-10-00
Pages
495-502
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1203527
Subset
IM
External Links
PubMed source DOI: 10.1093/genetics/120.2.495 PMC Full Text View journal details
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