Assignment of the gene determining human carbonic anhydrase, CAI, to chromosome 8.

Annals of human genetics ·Vol. 50 ·No. 2 ·1986-00-00 ·Pages 123-9

Edwards YH, Barlow JH, Konialis CP, Povey S, Butterworth PH

Abstract

A cDNA clone complementary to the mRNA encoding the rabbit erythrocyte specific carbonic anhydrase, CAI, has been used as probe for human CAI sequences in the analysis of DNA from panels of rodent/human somatic cell hybrids. The presence of the human CAI gene in all hybrids correlates with the presence of chromosome 8. Together with published mapping data, this assignment indicates that three CA loci are situated on chromosome 8.

MeSH Terms

Animals Carbonic Anhydrases/genetics Cells, Cultured Chromosome Mapping Chromosomes, Human, Pair 8 Cricetinae DNA Genes Humans Hybrid Cells Mice Rats

Chemicals

DNA Carbonic Anhydrases

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Edwards Y H

M.R.C. Human Biochemical Genetics Unit, Galton Laboratory, University College London.

Barlow J H

Konialis C P

Povey S

Butterworth P H

Article Info

Journal

Annals of human genetics

Abbr.

Ann Hum Genet

ISSN

0003-4800

DOI

10.1111/j.1469-1809.1986.tb01030.x

Published

1986-00-00

Pages

123-9

Language

English

Region

England

NLM ID

0416661

Subset

External Links

PubMed source DOI: 10.1111/j.1469-1809.1986.tb01030.x View journal details

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Assignment of the gene determining human carbonic anhydrase, CAI, to chromosome 8.

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