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PMID: 3114972 Published · ppublish ger Journal Article

[Classification of Gonococcus: auxanologic and serologic aspects using monoclonal antibodies].

Typisierung des Gonokokkus: Auxotypie und Serotypie mit monoklonalen Antikörpern.

Zeitschrift fur Hautkrankheiten ·Vol. 62 ·No. 14 ·1987-07-15 ·Pages 1086-100

Gründer K, Baumgartner A, Kohl PK, Tam MR, Knapp JS

Abstract

500 N. gonorrhoeae strains from the area of Lübeck/West Germany, collected in 1976-84, were auxologically and serologically classified by means of monoclonal antibodies from the Genetic Systems Corporation, Seattle, Washington (USA), against gonococcal outer membrane protein I. During the first years, auxological classification showed high proportions of AHU-strains (40%), which amounted to 20% over the total observation period. PPNG and DGI strains have characteristic type patterns. Our synopsis of serovars corresponds with the results obtained in a recent world-wide study. Combined auxological and serological classification shows two N. gonorrhoeae pools, 18% each, which cannot be further distinguished: AHU/A1 and prototrophic/B3. The advantages of the system have been proved in answering plain epidemiological questions. For further discrimination, an additional independent classification method might be useful.

MeSH Terms
Antibodies, Monoclonal Bacterial Outer Membrane Proteins/analysis Bacteriological Techniques Gonorrhea/microbiology Humans Male Neisseria gonorrhoeae/analysis,classification Serotyping
Chemicals
Antibodies, Monoclonal Bacterial Outer Membrane Proteins
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Gründer K
Baumgartner A
Kohl P K
Tam M R
Knapp J S
Article Info
Journal
Zeitschrift fur Hautkrankheiten
Abbr.
Z Hautkr
ISSN
0301-0481
Published
1987-07-15
Pages
1086-100
Language
ger
Region
Germany
NLM ID
0367576
Subset
IM
External Links
PubMed source
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