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PMID: 3072140 Published · ppublish English Journal Article Review

Clinical pharmacokinetics of doxycycline and minocycline.

Clinical pharmacokinetics ·Vol. 15 ·No. 6 ·1988-12-00 ·Pages 355-66

Saivin S, Houin G

Abstract

Doxycycline and minocycline are second-generation tetracyclines. They are readily absorbed, distributed throughout the organism as a function of their lipophilicity and eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.

MeSH Terms
Adolescent Adult Age Factors Aged Doxycycline/metabolism,pharmacokinetics Drug Interactions Female Humans Kidney Failure, Chronic/metabolism Male Minocycline/metabolism,pharmacokinetics Pregnancy Sex Factors Tetracyclines/pharmacokinetics Tissue Distribution
Chemicals
Tetracyclines Minocycline Doxycycline
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Saivin S
Unité de Pharmacocinétique Clinique, CHU Purpan, Toulouse, France.
Houin G
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Article Info
Journal
Clinical pharmacokinetics
Abbr.
Clin Pharmacokinet
ISSN
0312-5963
DOI
10.2165/00003088-198815060-00001
Published
1988-12-00
Pages
355-66
Language
English
Region
Switzerland
NLM ID
7606849
Subset
IM
External Links
PubMed source DOI: 10.2165/00003088-198815060-00001 View journal details
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