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题目:: Clonal origin of a T cell lymphoproliferative malignancy.
作者:: Stryckmans(P A),Debusscher(L),Heyder-Brückner(C),Heimann(R),Mandelbaum(I M),Wybran(J)
状态:: 发布时间1978-08-14 , 更新时间 2004-11-17
期刊:: Blood
摘要:: A woman with a T cell lymphoproliferative malignacy and heterozhgosity at the X chromosome-linked locus for glucose-6-phosphate dehydrogenase (G-6PD) isoenzymes was studied to find the clonal origin of her circulating neoplastic T cells. The red blood cells, polymorphonuclear cells, whole mononuclear cells, and T cell-depleted mononuclear cells contained both A and B isoenzymes of G-6-PD. In contrast, the tumor cells, separated by using their capacity to form rosettes with sheep red blood cells, contained only the B isoenzyme of G-6-PD. This observation strongly suggests the monoclonality of this T cell malignancy.
语言:: eng
DOI:

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