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PMID: 3050531 Published · ppublish English Journal Article Review

How eukaryotic transcriptional activators work.

Nature ·Vol. 335 ·No. 6192 ·1988-10-20 ·Pages 683-9

Ptashne M

Abstract

A specific protein, bound to DNA, can activate transcription of a wide array of genes in many eukaryotes. Further analysis suggests a general outline for how eukaryotic transcriptional activators function and are controlled.

MeSH Terms
Animals DNA-Binding Proteins/metabolism Drosophila/genetics Escherichia coli/genetics Eukaryotic Cells Gene Expression Regulation Plants/genetics Transcription, Genetic
Chemicals
DNA-Binding Proteins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Ptashne M
Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138.
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/335683a0
Published
1988-10-20
Pages
683-9
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/335683a0 View journal details
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