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PMID: 3038074 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Localization of the inosine triphosphatase locus (Itp) on chromosome 2 of the mouse.

Biochemical genetics ·Vol. 25 ·No. 3-4 ·1987-04-00 ·Pages 267-74

Taylor BA, Walls DM, Wimsatt MJ

Abstract

An electrophoretic variant of the enzyme inosine triphosphatase was found by screening inbred strains of mice. Strains with the slower-migrating variant include BALB/cJ, DBA/1J, and PL/J. The Itp locus was mapped between the beta-2-microglobulin (B2m) and the agouti (a) loci on chromosome 2. The mapping of Itp on chromosome 2 identifies a chromosomal segment that has been conserved since the divergence of lineages leading to mouse and man.

MeSH Terms
Animals Chromosome Mapping Genetic Linkage Genetic Variation Mice Mice, Inbred Strains/genetics Pyrophosphatases/genetics Species Specificity
Chemicals
Pyrophosphatases inosine triphosphatase
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Taylor B A
Walls D M
Wimsatt M J
References (14)
14 references, click to expand
  1. Chromosome maps of man and mouse II.
    Clin Genet. 1984 Jul;26(1):1-11 PMID: 6467650
  2. Standardized Nomenclature for Inbred Strains of Mice: eighth listing.
    Cancer Res. 1985 Mar;45(3):945-77 PMID: 3971387
  3. Genetic polymorphism of beta 2-microglobulin (B2m) maps to the H-3 region of chromosome 2.
    Immunogenetics. 1981;13(1-2):167-71 PMID: 6164636
  4. Gene map of the cow: conservation of linkage with mouse and man.
    J Hered. 1986 Jan-Feb;77(1):2-7 PMID: 3082971
  5. Location of the mouse beta 2-microglobulin gene B2m determined by linkage analysis.
    Immunogenetics. 1981;14(5):449-52 PMID: 6174441
  6. Genetic studies of human erythrocyte inosine triphosphatase.
    Biochem Genet. 1969 Jun;3(3):289-97 PMID: 4376397
  7. Lengths of chromosomal segments conserved since divergence of man and mouse.
    Proc Natl Acad Sci U S A. 1984 Feb;81(3):814-8 PMID: 6583681
  8. Evidence for two distinct c-src loci on human chromosomes 1 and 20.
    Nature. 1984 Nov 1-7;312(5989):70-1 PMID: 6092965
  9. Regional assignment of ADA and ITPA to mouse chromosome 2 (C1----ter). A demonstration of the conserved linkage of enzyme and proto-oncogene loci.
    J Hered. 1984 May-Jun;75(3):175-80 PMID: 6145740
  10. Chromosomal mapping of enzyme loci in the domestic cat: GSR to C2, ADA and ITPA to A3, and LDHA-ACP2 to D1.
    Cytogenet Cell Genet. 1986;41(2):114-20 PMID: 3007037
  11. Electrophoretically detected germinal mutations induced in the mouse by ethylnitrosourea.
    Proc Natl Acad Sci U S A. 1981 May;78(5):3138-41 PMID: 6942421
  12. Regional mapping of ADA and ITP on human chromosome 20: cytogenetic and somatic cell studies in an X/20 translocation.
    Cytogenet Cell Genet. 1980;26(1):28-35 PMID: 7371431
  13. Chromosomal mapping of murine c-fes and c-src genes.
    Mol Cell Biol. 1984 May;4(5):978-81 PMID: 6328281
  14. Deficiency of adenosine deaminase in the wasted mouse.
    Proc Natl Acad Sci U S A. 1986 Feb;83(3):693-5 PMID: 3456164
Article Info
Journal
Biochemical genetics
Abbr.
Biochem Genet
ISSN
0006-2928
DOI
10.1007/BF00499320
Published
1987-04-00
Pages
267-74
Language
English
Region
United States
NLM ID
0126611
Subset
IM
Grants
NCI NIH HHS · CA33093 · United States
NIGMS NIH HHS · GM18684 · United States
External Links
PubMed source DOI: 10.1007/BF00499320 View journal details
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