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Amiloride inhibition of the Na+-H+ exchanger in renal microvillus membrane vesicles.
Am J Physiol. 1981 Oct;241(4):F374-9
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Similarities in the mechanisms by which formyl-methionyl-leucyl-phenylalanine, arachidonic acid and leukotriene B4 increase calcium and sodium influxes in rabbit neutrophils.
Biochem Biophys Res Commun. 1981 Nov 16;103(1):227-32
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The ionic mechanism of intracellular pH regulation in crayfish neurones.
J Physiol. 1981 Jul;316:293-308
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Amiloride: a molecular probe of sodium transport in tissues and cells.
Am J Physiol. 1982 Mar;242(3):C131-45
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Ion pathways in renal brush border membranes.
Biochim Biophys Acta. 1982 Mar 8;685(3):260-72
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Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts.
J Biol Chem. 1982 Jul 25;257(14):8502-6
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Determination of the coupling ratio for Na+ -H+ exchange in renal microvillus membrane vesicles.
Biochim Biophys Acta. 1982 Jul 14;689(1):161-4
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The amiloride-sensitive Na+/H+ exchange system in skeletal muscle cells in culture.
J Biol Chem. 1982 Aug 25;257(16):9394-400
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Modifier role of internal H+ in activating the Na+-H+ exchanger in renal microvillus membrane vesicles.
Nature. 1982 Sep 9;299(5879):161-3
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Growth factor activation of an amiloride-sensitive Na+/H+ exchange system in quiescent fibroblasts: coupling to ribosomal protein S6 phosphorylation.
Proc Natl Acad Sci U S A. 1982 Jul;79(13):3935-9
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Volume regulation by Necturus gallbladder: apical Na+-H+ and Cl(-)-HCO-3 exchange.
Am J Physiol. 1982 Sep;243(3):C146-50
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Increased Na+-H+ exchange in brush border vesicles from dogs with renal failure.
Am J Physiol. 1982 Sep;243(3):F293-9
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Synergistic stimulation of DNA synthesis by cyclic AMP derivatives and growth factors in mouse 3T3 cells.
J Cell Physiol. 1982 Aug;112(2):243-50
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Amiloride blocks cell-free protein synthesis at levels attained inside cultured rat hepatocytes.
Biochem Biophys Res Commun. 1982 Sep 30;108(2):738-45
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CO2-stimulated NaCl absorption in the mouse renal cortical thick ascending limb of Henle. Evidence for synchronous Na +/H+ and Cl-/HCO3- exchange in apical plasma membranes.
J Gen Physiol. 1982 Nov;80(5):683-711
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Evidence for coupled sodium/hydrogen exchange in the rat superficial proximal convoluted tubule.
Pflugers Arch. 1982 Nov 11;395(3):186-9
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Na+/H+ antiport in Swiss 3T3 cells: mitogenic stimulation leads to cytoplasmic alkalinization.
Proc Natl Acad Sci U S A. 1982 Dec;79(24):7778-82
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Effect of the intracellular Ca+2 antagonist TMB-8 on serum-stimulated Na+ influx in human fibroblasts.
Biochem Biophys Res Commun. 1982 Dec 15;109(3):762-8
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Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins.
Cell. 1982 Nov;31(1):263-73
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Intracellular pH and the cell cycle of mitogen-stimulated murine lymphocytes.
J Cell Physiol. 1983 Jan;114(1):132-6
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Lys-bradykinin stimulates Na+ influx and DNA synthesis in cultured human fibroblasts.
Cell. 1983 Mar;32(3):979-85
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Biochemical characterization of the amiloride-sensitive Na+/H+ antiport in Chinese hamster lung fibroblasts.
J Biol Chem. 1983 Mar 25;258(6):3503-8
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Epidermal growth factor stimulates amiloride-sensitive 22Na+ uptake in A431 cells. Evidence for Na+/H+ exchange.
J Biol Chem. 1983 Apr 25;258(8):4883-9
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Analysis of angiotensin-stimulated sodium transport in cultured smooth muscle cells from rat aorta.
J Cell Physiol. 1983 Mar;114(3):284-90
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Stoichiometry and ion dependencies of the intracellular-pH-regulating mechanism in squid giant axons.
J Gen Physiol. 1983 Mar;81(3):373-99
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Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.
J Biol Chem. 1985 Jan 25;260(2):1155-9
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A bicarbonate-dependent process inhibitable by disulfonic stilbenes and a Na+/H+ exchange mediate 22Na+ uptake into cultured bovine corneal endothelium.
J Biol Chem. 1985 Jan 25;260(2):795-801
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A transient sodium-hydrogen exchange system induced by catecholamines in erythrocytes of rainbow trout, Salmo gairdneri.
J Physiol. 1984 Nov;356:21-31
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Parathyroid hormone and dibutyryl cAMP inhibit Na+/H+ exchange in renal brush border vesicles.
Am J Physiol. 1985 Feb;248(2 Pt 2):F212-8
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Glucocorticoid activation of Na+/H+ exchange in renal brush border vesicles: kinetic effects.
Am J Physiol. 1985 Feb;248(2 Pt 2):F233-9
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Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport.
Proc Natl Acad Sci U S A. 1985 Mar;82(5):1429-33
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Phorbol ester-induced changes of cytoplasmic pH in neutrophils: role of exocytosis in Na+-H+ exchange.
Am J Physiol. 1985 Mar;248(3 Pt 1):C379-86
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Demonstration of a Na+/H+ exchange activity in purified canine cardiac sarcolemmal vesicles.
J Biol Chem. 1985 Apr 25;260(8):4869-76
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Role of a Na+-dependent Cl-/HCO3- exchange in regulation of intracellular pH in fibroblasts.
J Biol Chem. 1985 Apr 25;260(8):4877-83
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Characterization of the Na+/H+ exchanger in human epidermoid carcinoma A431 vesicles.
J Cell Physiol. 1985 Jun;123(3):297-304
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Cyclic AMP inhibits Na+/H+ exchange at the apical membrane of Necturus gallbladder epithelium.
J Gen Physiol. 1985 Mar;85(3):409-29
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Defective jejunal brush-border Na+/H+ exchange: a cause of congenital secretory diarrhoea.
Lancet. 1985 May 11;1(8437):1066-9
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Sodium-dependent bicarbonate absorption by cortical thick ascending limb of rat kidney.
Am J Physiol. 1985 Jun;248(6 Pt 2):F821-9
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Coupled Na+-H+ exchange in isolated acinar cells from rat exocrine pancreas.
Am J Physiol. 1985 Jul;249(1 Pt 1):G125-36
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Sodium and chloride transport across rabbit ileal brush border. II. Evidence for Cl-HCO3 exchange and mechanism of coupling.
Am J Physiol. 1985 Aug;249(2 Pt 1):G236-45
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Chloride/formate exchange with formic acid recycling: a mechanism of active chloride transport across epithelial membranes.
Proc Natl Acad Sci U S A. 1985 Sep;82(18):6362-5
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Interrelationships among quinidine, amiloride, and lithium as inhibitors of the renal Na+-H+ exchanger.
J Biol Chem. 1985 Oct 15;260(23):12586-92
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Intracellular pH modulates the generation of superoxide radicals by human neutrophils.
J Clin Invest. 1985 Sep;76(3):1079-89
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Red-cell lithium-sodium countertransport and renal lithium clearance in hypertension.
N Engl J Med. 1986 Jan 23;314(4):198-201
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Cellular sodium transport in essential hypertension.
N Engl J Med. 1986 Jan 23;314(4):222-9
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Inactivation of the renal microvillus membrane Na+-H+ exchanger by histidine-specific reagents.
J Biol Chem. 1986 Jan 25;261(3):1120-5
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Sodium-hydrogen exchange and glucose transport in renal microvillus membrane vesicles from rats with diabetes mellitus.
J Clin Invest. 1986 Mar;77(3):724-33
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Mechanisms of regulation of the Na+/H+ exchanger.
J Membr Biol. 1986;90(1):1-12
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Volume regulation by Amphiuma red blood cells. The membrane potential and its implications regarding the nature of the ion-flux pathways.
J Gen Physiol. 1980 Dec;76(6):683-708
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Micropuncture analysis of the cellular mechanisms of electrolyte secretion by the in vitro rabbit pancreas.
J Gen Physiol. 1975 Jan;65(1):22-45
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Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidney.
Biochem J. 1976 Mar 15;154(3):597-604
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Intracellular pH and activation of sea urchin eggs after fertilisation.
Nature. 1976 Aug 19;262(5570):661-4
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Effect of bicarbonate and other buffers on choroid plexus Na+/K+pump.
Biochim Biophys Acta. 1977 Aug 1;468(3):486-9
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The role of bicarbonate, chloride and sodium ions in the regulation of intracellular pH in snail neurones.
J Physiol. 1977 Dec;273(1):317-38
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Serum stimulates the Na+,K+ pump in quiescent fibroblasts by increasing Na+ entry.
Proc Natl Acad Sci U S A. 1978 Nov;75(11):5560-4
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Intracellular pH and the sodium requirement at fertilisation.
Nature. 1979 Nov 1;282(5734):87-9
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Increased sodium ion influx is necessary to initiate rat hepatocyte proliferation.
Cell. 1979 Sep;18(1):153-63
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Elevation of intracellular pH by insulin in frog skeletal muscle.
Biochem Biophys Res Commun. 1979 Dec 14;91(3):900-4
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Properties of the Na+-H+ exchanger in renal microvillus membrane vesicles.
Am J Physiol. 1980 Jun;238(6):F461-9
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Vasopressin rapidly stimulates Na entry and Na-K pump activity in quiescent cultures of mouse 3T3 cells.
J Cell Physiol. 1980 Oct;105(1):153-62
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Interactions between the regulation of the intracellular pH and sodium activity of sheep cardiac Purkinje fibres.
J Physiol. 1980 Jul;304:471-88
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Sodium-dependent activation of sea urchin spermatozoa by speract and monensin.
J Biol Chem. 1981 Mar 10;256(5):2235-41
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Determination of disequilibrium pH in the rat kidney in vivo: evidence of hydrogen secretion.
Am J Physiol. 1981 Feb;240(2):F138-46
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Melittin stimulates Na entry, Na-K pump activity and DNA synthesis in quiescent cultures of mouse cells.
Cell. 1981 Mar;23(3):781-8
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Rapid ionic events and the initiation of growth in serum-stimulated neuroblastoma cells.
Cell. 1981 Mar;23(3):789-98
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Interaction of NH4+ and Li+ with the renal microvillus membrane Na+-H+ exchanger.
Am J Physiol. 1981 Nov;241(5):C220-6
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Sodium/proton exchange in mouse neuroblastoma cells.
J Biol Chem. 1981 Dec 25;256(24):12883-7
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Volume-responsive sodium movements in dog red blood cells.
Am J Physiol. 1983 May;244(5):C324-30
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Microfluorometric monitoring of pHi in cultured heart cells: Na+-H+ exchange.
Am J Physiol. 1983 May;244(5):C422-8
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The amiloride-sensitive Na+/H+ antiport in 3T3 fibroblasts.
J Biol Chem. 1983 May 25;258(10):6272-6
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Interaction of external H+ with the Na+-H+ exchanger in renal microvillus membrane vesicles.
J Biol Chem. 1983 Jun 10;258(11):6767-71
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Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells.
J Cell Biol. 1983 Jul;97(1):92-8
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Characteristics of an amiloride-sensitive sodium entry pathway in cultured rodent glial and neuroblastoma cells.
J Cell Physiol. 1983 Aug;116(2):213-20
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Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts.
Nature. 1983 Aug 18-24;304(5927):645-8
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Metabolic acidosis and parathyroidectomy increase Na+-H+ exchange in brush border vesicles.
Am J Physiol. 1983 Aug;245(2):F217-22
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Efflux of 45Ca2+ from human fibroblasts in response to serum or growth factors.
J Cell Physiol. 1983 Oct;117(1):23-9
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Sodium transport in capillaries isolated from rat brain.
J Neurochem. 1983 Oct;41(4):1150-7
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Platelet-derived growth factor stimulates Na+/H+ exchange and induces cytoplasmic alkalinization in NR6 cells.
Proc Natl Acad Sci U S A. 1983 Oct;80(20):6224-8
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Activation of Na+/H+ exchange by epidermal growth factor elevates intracellular pH in A431 cells.
J Biol Chem. 1983 Oct 25;258(20):12644-53
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Activation of Na+/H+ exchange in lymphocytes by osmotically induced volume changes and by cytoplasmic acidification.
J Gen Physiol. 1983 Nov;82(5):619-38
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Mechanisms of active H+ secretion in the proximal tubule.
Am J Physiol. 1983 Dec;245(6):F647-59
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Cation gradient dependence of the steps in thrombin stimulation of human platelets.
J Biol Chem. 1984 Feb 10;259(3):1502-8
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Na+-H+ exchange and Na+ entry across the apical membrane of Necturus gallbladder.
J Gen Physiol. 1984 Jan;83(1):57-74
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Na+-H+ exchange activity in renal brush border membrane vesicles in response to metabolic acidosis: The role of glucocorticoids.
Proc Natl Acad Sci U S A. 1984 Jan;81(2):630-4
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Evidence for the role of phosphorylase kinase, protein kinase C, and other Ca2+-sensitive protein kinases in the response of hepatocytes to angiotensin II and vasopressin.
J Biol Chem. 1984 Mar 10;259(5):3283-92
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Extracellular Na+ and initiation of DNA synthesis: role of intracellular pH and K+.
J Cell Biol. 1984 Mar;98(3):1082-9
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Proton transport and cell function.
J Clin Invest. 1984 Feb;73(2):285-90
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Growth factor action and intracellular pH regulation in fibroblasts. Evidence for a major role of the Na+/H+ antiport.
J Biol Chem. 1984 May 10;259(9):5809-15
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Cytoplasmic pH regulation in thymic lymphocytes by an amiloride-sensitive Na+/H+ antiport.
J Gen Physiol. 1984 Mar;83(3):341-69
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Metabolic regulation via intracellular pH.
Am J Physiol. 1984 Apr;246(4 Pt 2):R409-38
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Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange.
J Biol Chem. 1984 Jun 10;259(11):7056-60
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The regulation of cytoplasmic pH in human fibroblasts.
J Biol Chem. 1984 Jun 25;259(12):7563-9
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Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.
J Cell Biol. 1984 Jul;99(1 Pt 1):340-3
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A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH.
Proc Natl Acad Sci U S A. 1984 Aug;81(15):4833-7
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Increased Vmax for Na+/H+ antiporter activity in proximal tubule brush border vesicles from rabbits with metabolic acidosis.
Am J Physiol. 1984 Aug;247(2 Pt 2):F339-43
PMID: 6087681
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Activation of amiloride-sensitive sodium transport in C6 glioma cells.
J Neurochem. 1984 Oct;43(4):1098-105
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Turnover of inositol phospholipids and signal transduction.
Science. 1984 Sep 21;225(4668):1365-70
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Inhibition of epidermal growth factor-induced mitogenesis by amiloride and an analog: evidence against a requirement for Na+/H+ exchange.
Proc Natl Acad Sci U S A. 1984 Nov;81(21):6762-6
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Tyrosine protein kinases.
Adv Cyclic Nucleotide Protein Phosphorylation Res. 1984;18:195-226
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Na regulates growth of kidney epithelial cells induced by lowering extracellular K concentration.
Am J Physiol. 1984 Nov;247(5 Pt 1):C321-6
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Platelet-derived growth factor stimulates Na+ influx in vascular smooth muscle cells.
Am J Physiol. 1984 Nov;247(5 Pt 1):C501-5
PMID: 6093577
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22Na+ fluxes in thymic lymphocytes. I. Na+/Na+ and Na+/H+ exchange through an amiloride-insensitive pathway.
J Gen Physiol. 1984 Oct;84(4):565-84
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Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH.
Nature. 1984 Nov 22-28;312(5992):371-4
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Cl- transport via anion exchange in Necturus renal microvillus membranes.
Am J Physiol. 1984 Dec;247(6 Pt 2):F888-95
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Adaptation of Na+-H+ exchange in renal microvillus membrane vesicles. Role of dietary protein and uninephrectomy.
J Clin Invest. 1984 Dec;74(6):1979-87
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Chemical modification of the Na+/H+ exchanger of thymic lymphocytes. Inhibition by N-ethylmaleimide.
Biochim Biophys Acta. 1985 Jan 10;812(1):213-22
PMID: 2981544