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PMID: 3016454 Published · ppublish English Journal Article

Polymorphisms in the apolipoprotein AI-CIII gene complex.

Molecular biology & medicine ·Vol. 3 ·No. 3 ·1986-06-00 ·Pages 213-28

Coleman RT, Gonzalez PA, Funke H, Assmann G, Levy-Wilson B, Frossard PM

Abstract

We report the presence of five restriction fragment length polymorphisms in the apolipoprotein AI-CIII (apo AI-CIII) gene complex as well as their respective allelic frequencies in a German population (pi) that we studied: an SstI (BanII) polymorphism in the 3' non-coding region of apo CIII q1(pi) = 0.13); an MspI polymorphism in the third intron of apo AI (q2(pi) = 0.12); a PvuII polymorphism in the first intron of apo CIII (q3(pi) = 0.30); and two XmnI polymorphisms in the 5' side of apo AI (q4(pi) = 0.20 and q5(pi) = 0.05).

MeSH Terms
Apolipoprotein A-I Apolipoprotein C-III Apolipoproteins A/genetics Apolipoproteins C/genetics Base Sequence DNA/genetics DNA Restriction Enzymes Humans Nucleic Acid Hybridization Polymorphism, Genetic Protein Biosynthesis
Chemicals
Apolipoprotein A-I Apolipoprotein C-III Apolipoproteins A Apolipoproteins C DNA DNA Restriction Enzymes
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Coleman R T
Gonzalez P A
Funke H
Assmann G
Levy-Wilson B
Frossard P M
Article Info
Journal
Molecular biology & medicine
Abbr.
Mol Biol Med
ISSN
0735-1313
Published
1986-06-00
Pages
213-28
Language
English
Region
England
NLM ID
8403879
Subset
IM
External Links
PubMed source
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