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PMID: 3012780 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Viral shedding and transmission between hosts determined by reovirus L2 gene.

Science (New York, N.Y.) ·Vol. 232 ·No. 4758 ·1986-06-27 ·Pages 1635-8

Keroack M, Fields BN

Abstract

Two reovirus isolates (type 1 Lang and type 3 Dearing) differ in their transmissibility between littermates of newborn mice. They also differ in the amounts of virus excreted by the gastrointestinal tract. With the use of reassortant viruses, these properties were mapped to the L2 gene. Thus environmental spread of reovirus is a genetic property.

MeSH Terms

Animals Animals, Newborn/microbiology Digestive System/microbiology Genes, Viral Mammalian orthoreovirus 3/physiology Mice Reoviridae/physiology Reoviridae Infections/microbiology,transmission

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Keroack M

Fields B N

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.3012780

Published

1986-06-27

Pages

1635-8

Language

English

Region

United States

NLM ID

0404511

Subset

Grants

NIAID NIH HHS · 5R01 AI13178 · United States

External Links

PubMed source DOI: 10.1126/science.3012780 View journal details

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Viral shedding and transmission between hosts determined by reovirus L2 gene.

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