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PMID: 3006483 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Human mitochondrial DNA types in two Israeli populations--a comparative study at the DNA level.

American journal of human genetics ·Vol. 38 ·No. 3 ·1986-03-00 ·Pages 341-51

Bonné-Tamir B, Johnson MJ, Natali A, Wallace DC, Cavalli-Sforza LL

Abstract

Variations in human mtDNA restriction endonuclease fragment patterns were investigated in a sample number of 81 Israelis--Jews and Arabs--using total blood cell DNA. Eight new morphs were observed using five enzymes: HpaI, BamHI, HaeII, MspI, and AvaII. Of the 18 different combinations of fragment patterns (mtDNA types), only three were shared by both groups, but with striking frequency differences. The Arab sample disclosed "African" characteristics and was found to be slightly more polymorphic than the Israeli sample. One of the new types filled a "missing link" originally postulated in a phylogeny of mtDNA human types.

MeSH Terms
DNA Restriction Enzymes DNA, Mitochondrial/genetics Ethnicity Genetic Markers Humans Israel Jews Phylogeny Polymorphism, Genetic
Chemicals
DNA, Mitochondrial Genetic Markers DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Bonné-Tamir B
Johnson M J
Natali A
Wallace D C
Cavalli-Sforza L L
References (12)
12 references, click to expand
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Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1986-03-00
Pages
341-51
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1684768
Subset
IM
Grants
NIGMS NIH HHS · GM-20467 · United States
External Links
PubMed source PMC Full Text View journal details
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