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PMID: 3005204 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Myristylation of gag protein in human T-cell leukemia virus type-I and type-II.

Japanese journal of cancer research : Gann ·Vol. 76 ·No. 12 ·1985-12-00 ·Pages 1132-5

Ootsuyama Y, Shimotohno K, Miwa M, Oroszlan S, Sugimura T

Abstract

We found that p19gag of HTLV-I and p23gag of HTLV-II are myristylated. The p28, which is immunologically cross-reactive with monoclonal antibody against p19gag of HTLV-I was also shown to be myristylated in the HTLV-I-infected cell lines MT-2 and HUT102. However, no myristylated p28 was found in HTLV-II-infected cell lines, Mo and Ton1.

MeSH Terms
Antibodies, Monoclonal Deltaretrovirus/metabolism Gene Products, gag Myristates/metabolism Myristic Acids/metabolism Palmitates/metabolism Protein Processing, Post-Translational Retroviridae Proteins/metabolism
Chemicals
Antibodies, Monoclonal Gene Products, gag Myristates Myristic Acids Palmitates Retroviridae Proteins
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Ootsuyama Y
Shimotohno K
Miwa M
Oroszlan S
Sugimura T
Article Info
Journal
Japanese journal of cancer research : Gann
Abbr.
Jpn J Cancer Res
ISSN
0910-5050
Published
1985-12-00
Pages
1132-5
Language
English
Region
Japan
NLM ID
8509412
Subset
IM
External Links
PubMed source
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