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PMID: 30030517 Published · ppublish English Journal Article Comment

GPCR signaling: conformational activation of arrestins.

Cell research ·Vol. 28 ·No. 8 ·2018-00-00 ·Pages 783-784

Kahsai AW, Pani B, Lefkowitz RJ

Abstract

暂无摘要

MeSH Terms
Arrestin Arrestins Receptors, G-Protein-Coupled beta-Arrestins
Chemicals
Arrestin Arrestins Receptors, G-Protein-Coupled beta-Arrestins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Kahsai Alem W
Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA.
Pani Biswaranjan ORCID
Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA.
Lefkowitz Robert J
Department of Medicine, Duke University Medical Center, Durham, NC, 27710, USA. lefko001@receptor-biol.duke.edu. | Department of Biochemistry, Duke University Medical Center, Durham, NC, 27710, USA. lefko001@receptor-biol.duke.edu. | Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC, 27710, USA. lefko001@receptor-biol.duke.edu.
References (12)
12 references, click to expand
  1. Visualization of arrestin recruitment by a G-protein-coupled receptor.
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  2. The structural basis of arrestin-mediated regulation of G-protein-coupled receptors.
    Pharmacol Ther. 2006 Jun;110(3):465-502 PMID: 16460808
  3. The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.
    Pharmacol Rev. 2017 Jul;69(3):256-297 PMID: 28626043
  4. Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling.
    Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1442-7 PMID: 15671181
  5. β-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation.
    Nat Cell Biol. 2016 Mar;18(3):303-10 PMID: 26829388
  6. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
    Nature. 2015 Jul 30;523(7562):561-7 PMID: 26200343
  7. A brief history of G-protein coupled receptors (Nobel Lecture).
    Angew Chem Int Ed Engl. 2013 Jun 17;52(25):6366-78 PMID: 23650015
  8. Molecular mechanism of GPCR-mediated arrestin activation.
    Nature. 2018 May;557(7705):452-456 PMID: 29720655
  9. Catalytic activation of β-arrestin by GPCRs.
    Nature. 2018 May;557(7705):381-386 PMID: 29720660
  10. Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors.
    J Biol Chem. 2000 Jun 2;275(22):17201-10 PMID: 10748214
  11. G proteins: transducers of receptor-generated signals.
    Annu Rev Biochem. 1987;56:615-49 PMID: 3113327
  12. Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis.
    Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2562-2567 PMID: 28223524
Article Info
Journal
Cell research
Abbr.
Cell Res
ISSN
1748-7838
DOI
10.1038/s41422-018-0067-x
Email
lefko001@receptor-biol.duke.edu
Published
2018-00-00
Pages
783-784
Language
English
Region
England
NLM ID
9425763
PMCID
PMC6082894
Corrections
CommentOn
PMID: 29720655
CommentOn
PMID: 29720660
External Links
PubMed source DOI: 10.1038/s41422-018-0067-x PMC Full Text View journal details
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