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PMID: 2993242 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Regulation of CDP-diacylglycerol synthase activity in Saccharomyces cerevisiae.

Journal of bacteriology ·Vol. 163 ·No. 3 ·1985-09-00 ·Pages 1265-6

Homann MJ, Henry SA, Carman GM

Abstract

The addition of ethanolamine or choline to inositol-containing growth medium resulted in a reduction of CTP:phosphatidate cytidylyltransferase (CDP-diacylglycerol synthase; EC 2.7.7.41) activity in Saccharomyces cerevisiae. The reduction of activity did not occur in the absence of inositol. CDP-diacylglycerol synthase activity was not regulated in a S. cerevisiae mutant strain (opi1; an inositol biosynthesis regulatory mutant) by the addition of phospholipid precursors to the growth medium.

MeSH Terms
Choline/pharmacology Ethanolamine Ethanolamines/pharmacology Kinetics Nucleotidyltransferases/metabolism Saccharomyces cerevisiae/enzymology,growth & development Tritium
Chemicals
Ethanolamines Tritium Ethanolamine Nucleotidyltransferases phosphatidate cytidylyltransferase Choline
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Homann M J
Henry S A
Carman G M
References (15)
15 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.163.3.1265-1266.1985
Published
1985-09-00
Pages
1265-6
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC219270
Subset
IM
Grants
NIGMS NIH HHS · GM-11301 · United States
NIGMS NIH HHS · GM-19629 · United States
NIGMS NIH HHS · GM-28140 · United States
External Links
PubMed source DOI: 10.1128/jb.163.3.1265-1266.1985 PMC Full Text View journal details
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