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PMID: 2981412 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Construction of linkage maps with DNA markers for human chromosomes.

Nature ·Vol. 313 ·No. 5998 ·1985-00-00 ·Pages 101-5

White R, Leppert M, Bishop DT, Barker D, Berkowitz J, Brown C, Callahan P, Holm T, Jerominski L

Abstract

DNA markers and sampling of three-generation families can be used to construct complete linkage maps of human chromosomes. This is important in mapping disease loci and in determining the genetic or environmental component of a disease.

MeSH Terms
Chromosome Mapping Chromosomes, Human DNA Restriction Enzymes Genetic Diseases, Inborn/genetics Genetic Linkage Heterozygote Humans Pedigree Recombination, Genetic
Chemicals
DNA Restriction Enzymes
Authors & Affiliations
9 authors, click to expand affiliations / ORCID
White R
Leppert M
Bishop D T
Barker D
Berkowitz J
Brown C
Callahan P
Holm T
Jerominski L
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/313101a0
Published
1985-00-00
Pages
101-5
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/313101a0 View journal details
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