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PMID: 2938003 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Characterisation of a repetitive DNA sequence from the malaria parasite, Plasmodium falciparum.

Molecular and biochemical parasitology ·Vol. 18 ·No. 1 ·1986-01-00 ·Pages 89-101

Oquendo P, Goman M, Mackay M, Langsley G, Walliker D, Scaife J

Abstract

A repetitive DNA fragment cloned from the malaria parasite, Plasmodium falciparum, has been analysed. It contains a 21 base pair sequence which occurs in multiple tandem repeats. Two clusters of the same repeat are found in opposite orientations on the same DNA fragment. The repetitive DNA provides an additional way to distinguish between different strains of parasite by hybridisation to genomic blots and may serve as a species-specific probe for diagnosis.

MeSH Terms
Animals Bacteriophage lambda/genetics Cloning, Molecular DNA/analysis,isolation & purification Nucleic Acid Hybridization Plasmodium falciparum/genetics Repetitive Sequences, Nucleic Acid
Chemicals
DNA
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Oquendo P
Goman M
Mackay M
Langsley G
Walliker D
Scaife J
Article Info
Journal
Molecular and biochemical parasitology
Abbr.
Mol Biochem Parasitol
ISSN
0166-6851
Published
1986-01-00
Pages
89-101
Language
English
Region
Netherlands
NLM ID
8006324
Subset
IM
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