Home LiteratureArticle Details
PMID: 2933030 Published · ppublish English Journal Article

Mechanism of action of rabbit liver phosphoglucomutase.

The Biochemical journal ·Vol. 230 ·No. 3 ·1985-09-15 ·Pages 791-5

Jamil H, Clarke JB

Abstract

Induced-transport tests with comparatively undegraded rabbit liver phosphoglucomutase show that the enzyme possesses a phosphoenzyme mechanism and that any interconversion of phosphoenzyme forms is very rapid. A relatively stable 32P-labelled phosphoenzyme was isolated, which exchanged label rapidly with substrates. The phospho group appears to be bonded to a serine residue on the enzyme.

MeSH Terms
Animals Biological Transport Kinetics Liver/enzymology Models, Biological Phosphoglucomutase/metabolism Rabbits
Chemicals
Phosphoglucomutase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Jamil H
Clarke J B
References (18)
18 references, click to expand
  1. Apparent change in reaction mechanism of phosphoglycerate mutase induced by salt.
    Biochem Biophys Res Commun. 1966 Jan 24;22(2):200-5 PMID: 5902293
  2. Properties of the phosphoprotein-phosphoglyceric mutase.
    J Biol Chem. 1960 Apr;235:895-901 PMID: 14433335
  3. The presence of D-glucose 1,6-diphosphate hydrolyzing enzymes.
    J Biochem. 1966 Apr;59(4):427-9 PMID: 4289049
  4. Influence of ionic strength on apparent reaction mechanism of phosphoglycerate mutase.
    Biochemistry. 1966 Oct;5(10):3116-22 PMID: 5971826
  5. The mechanism of the phosphoglucomutase reaction. Studies on rabbit muscle phosphoglucomutase with flux techniques.
    Biochem J. 1968 Nov;110(2):161-80 PMID: 5726186
  6. Evidence for a phosphohistidine protein intermediate in the phosphoglycerate mutase reaction.
    Arch Biochem Biophys. 1970 Oct;140(2):508-13 PMID: 5528743
  7. Differentiation of the PGM 2 locus isozymes from those of PGM 1 and PGM 3 in terms of phosphopentomutase activity.
    Ann Hum Genet. 1972 Apr;35(4):445-54 PMID: 4116322
  8. The synthesis and purification of (gamma-32P)-adenosine triphosphate with high specific activity.
    J Biol Chem. 1973 Dec 10;248(23):8319-21 PMID: 4752959
  9. Preparation and properties of a phosphoenzyme from the phosphoglucomutase of Micrococcus lysodeikticus.
    Biochem J. 1974 Mar;137(3):463-7 PMID: 4472509
  10. The mechanism of phosphoglucomutase from Micrococcus lysodeikticus.
    Biochem J. 1974 Mar;137(3):453-61 PMID: 4472922
  11. An analysis of the substrate-induced rate effect in the phosphoglucomutase system.
    Biochemistry. 1976 Sep 7;15(18):4006-17 PMID: 963019
  12. Regulation of glucose 1,6-bisphosphate level in liver. III. Purification and properties of bovine glucose 1,6-bisphosphate synthase.
    J Biochem. 1978 Jun;83(6):1721-30 PMID: 670163
  13. Structural comparisons among the central complexes in the phosphoglucomutase system by means of spectral techniques.
    Biochemistry. 1980 Feb 19;19(4):751-9 PMID: 6444518
  14. A stereochemical investigation of phosphoryl transfer catalysed by phosphoglucomutase by the use of alpha-D-glucose 1-[(S)-16O,17O,18O]phosphate.
    Biochem J. 1981 Dec 1;199(3):693-8 PMID: 6462135
  15. Properties of the phosphorylated active site of phosphoglucomutase.
    J Biol Chem. 1957 Sep;228(1):419-31 PMID: 13475328
  16. A KINETIC STUDY OF THE PHOSPHOGLUCOMUTASE PATHWAY.
    J Biol Chem. 1964 Apr;239:1228-36 PMID: 14165931
  17. THE PHOSPHOGLUCOMUTASE PATHWAY. AN INVESTIGATION OF PHOSPHO-ENZYME ISOMERIZATION.
    J Biol Chem. 1964 Nov;239:3935-41 PMID: 14257629
  18. Phosphoglucomutase. 3. Purification and properties of phosphoglucomutases from flounder and shark muscle.
    J Biol Chem. 1966 Sep 10;241(17):3940-8 PMID: 5920804
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
Published
1985-09-15
Pages
791-5
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1152685
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com